Korean J Dermatol.  1987 Aug;25(4):500-505.

Quantiative Study of Epidermal Langerhans Cell in Vitiligo

• Park YK
• Hann SK

Abstract

Report. about numeric change of LC between vitiliginous skin(VS) and adjacent normal appering skin (ANAS) are hard to find, Epidermal Langerhans Cell (LC) dersities in VS and ANAS were studied in 18 patient with generalized vitiligo. Adenosine triphosphatase(ATPase) stain was used to characterize LC. Epidermal LC densities were calculated by means of an eye piece reticule and expressed per mm. The results were as follows; 1. The was significant body site variation of LC densities in ANAS and the range of densities of LC per mm were from 668+165 to 1,241 _3 and the mean density of LC per mm was 944+258. 3. The LC densities of VS was similar to that of ANAS(p: not significant). In conclusion quantiative change of epidermal LC in vitiligo doesn't seem to have significant relation with pathogenesis of vitiligo.

Keyword

Langerhans cells; Vitiligo; ATPase stain

MeSH Terms

Adenosine
Humans
Langerhans Cells
Skin
Vitiligo*
Adenosine