Korean J Dermatol.  1987 Aug;25(4):451-459.

Histopathologic Study of Drug - Induced Morbiliform Eruption and Erythema Multiforme

• Cho KH
• Shin KS

Abstract

A histopathological observation of drug-induced morbilliform eruption and erythema multiforme was made on 32 patients with drug eruption, We found that many histopathologic features of drug-induced morbilliform eruption of basal cell layer with infiltration of derrnoepidermal junction and necrosis of epidermal keratinocyte were similar to those of drug induced erythema multiforme. Therefore, it seems possible to regard the histopathologic features of druginduced morbilliform eruption and erythema multiforrne as a cornmon tissuc reaction with spectral expression.

Keyword

Drug; Morbilliform eruption; Erythema multiforme; Histopathologic feature

MeSH Terms

Drug Eruptions
Erythema Multiforme*
Erythema*
Humans
Keratinocytes
Necrosis