Korean Circ J.  1991 Dec;21(6):1219-1224. 10.4070/kcj.1991.21.6.1219.

Clinical Observation on Effect of Amlodipine in Angina Pectoris

• Kim HS
• Yang JY
• Jang YS
• Tahk SJ
• Shim WH
• Cho SY
• Kim SS

• KMID: 2229005
• DOI: http://doi.org/10.4070/kcj.1991.21.6.1219

Abstract

We evaluated the clinical effects of amlodipine in 10 patients(7 male and 3 female) with angina pectoris in terms of the effect on the anginal pain, hemodynamic changes and side effects. The results obtained were as follows; 1) The clinical improvement was obsebed in 8(80.8%) of 10 and 9(88.9%) of 9 patients at 2 and 10 weeks after oral amlodipine. 2) The systolic and diastolic blood pressure was decreased significantly(136.0+/-16.5mmHg vs 117.0+/-10.6mmHg, p<0.01 and 85.0+/-9.7mmHg vs 75.0+/-5.3mmHg, p<0.01 respectively) but the heart rate was indepentent of amlodipine administration. 3) The adverse effects of amlodipine were as headache in 3, facial flushing in 3, palpitation, dizziness, urinary difficulty in 1 respectively and one of them discontinued amlodipine due to severe palpitation and facial flushing.

MeSH Terms

Amlodipine*
Angina Pectoris*
Blood Pressure
Dizziness
Flushing
Headache
Heart Rate
Hemodynamics
Humans
Male
Amlodipine