Korean Circ J.  1982 Dec;12(2):193-197. 10.4070/kcj.1982.12.2.193.

Clinical Observation on Effect of Diltiazem(Herben(R)) in Angina Pectoris

Abstract

We evaluate the effects of diltiazem in 19 patients with ischemic heart disease (15 patients) of classical anginal pectoris & 4 patients of variant angina) by means of clinical status & electrocardiographic changes and obtain the results as follows: 1. The pulse rate & blood pressure were decreased by diltiazem slightly but these decreases were not significant in statistical meaning. 2. Diltiazem administration of 4 weeks duration normalized EKG completely in 4 patients & partially in 3 patients among the 13 patients who showed abnormal resting EKG initially. 3. All 19 patients who received diltiazem showed clinical improvement; 9 patients had excellent responses, 7 patients good responses & 3 patients fair responses. 4. Diltiazem had side effects in 3 patients, drowsiness, mild euphoria & possibly tolerance respectively in each patients.


MeSH Terms

Angina Pectoris*
Blood Pressure
Diltiazem
Electrocardiography
Euphoria
Heart Rate
Humans
Myocardial Ischemia
Sleep Stages
Diltiazem
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