Korean J Crit Care Med.  2010 Jun;25(2):89-92. 10.4266/kjccm.2010.25.2.89.

Successful Heart Transplantation after Dobutamine, Glucose-insulin-potassium, and Hormone Therapy in a Hemodynamically Unstable Cadaveric Heart Donor: A Case Report

Affiliations
  • 1Department of Anaesthesiology and Pain Medicine, Anaesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. nswksj@yuhs.ac
  • 2Division of Pediatric Cardiac Surgery, Asan Midical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

The major limitation to heart transplantation is the shortage of donor organs. In order to increase the cardiac donor pool, it is important to maintain stable hemodynamics and closely monitor cardiac function in cadaveric organ donors or potent donors. Recently, management of a potential cardiac donor pool has focused on aggressive hemodynamic management protocols and dobutamine stress echocardiography. In our case, management with low dose dobutamine, glucose-insulin-potassium (GIK), and hormone therapy reversed heart failure following brain death and the heart was successfully transplanted. We suggest that aggressive hemodynamic management with low-dose dobutamine, GIK, and hormone therapy can result in the recruitment of more cadaveric hearts in marginal conditions.

Keyword

brain death; cardiomyopathy; echocardiography

MeSH Terms

Brain Death
Cadaver
Cardiomyopathies
Dobutamine
Echocardiography
Echocardiography, Stress
Heart
Heart Failure
Heart Transplantation
Hemodynamics
Humans
Organothiophosphorus Compounds
Tissue Donors
Transplants
Dobutamine
Organothiophosphorus Compounds
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