Korean J Cytopathol.  1996 Jun;7(1):97-102.

Fine Needle Aspiration Cytology of Metastatic Pulmonary Seminoma: A Cese Report

• Jeong HS
• Lee GK
• Kim WJ
• Earm JH
• Song HG

Abstract

Fine needle aspiration cytologyof a pulmonary mass was performed on a 51-year-old man who had a left testicular mass. Cytologic features were composed of a homogeneous population of malignant cells associated with a background of foamy and lacelike material. The cellular features were characterized by monomorphous cell proliferation of relatively regular large cells, generally isolated or grouped. Occasionally, fine branching stroma with large tumor cells and scanty lymphocytes were noted. The tumor cells had a round, regular nucleus, prominent round nucleoli, and a thin rim of cytoplasm containing large vacuoles or lacunae filled with glycogen. The fine needle aspiration cytologic diagnosis was highly consistent with metastatic seminoma from testis and less likely primary or other metastatic carcinoma. The diagnosis of resected testicular mass was classic seminoma. Despite the fact that cytopathologists were not familiar with diagnosis of seminoma due to clinician's lack of interest in fine needle aspiration cytology of germ cell tumors including seminoma, it appears that a diagnosis of this tumor should not be problematic in cytologic material if specific histologic criteria are applied.

Keyword

Fine needle aspiration cytology; Seminoma; Metastasis; Lung

MeSH Terms

Biopsy, Fine-Needle*
Cell Proliferation
Cytoplasm
Diagnosis
Glycogen
Humans
Lung
Lymphocytes
Middle Aged
Neoplasm Metastasis
Neoplasms, Germ Cell and Embryonal
Seminoma*
Testis
Vacuoles
Glycogen