J Rhinol.
2003 Nov;10(1, 2):53-56.
Two Cases of Cholesterol Granuloma in Ethmoid Sinuses
- Affiliations
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- 1Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Daejeon, Korea. sw43857@cnu.ac.kr
Abstract
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Cholesterol granuloma is a chronic inflammatory process associated foreign body reaction to hemorrhage-related cholesterol crystals that have been precipitated in the tissue. Cholesterol granuloma of the middle ear usually accompany chronic middleear diseases with diminished ventilation. However, cholesterol granuloma of the paranasal sinus is rare. Impaired drainage, hemorrhage, inadequate ventilation play a significant role in its pathogenesis. Symptoms are diverse according to the location and size of the lesion, and also to the presence of wall erosion of the affected sinus. Diagnosis should be made with his tologic investigation of the operative specimen. Radical clearance of the disease using an endoscopic approach and drainage of the affected sinus cavity is the treatment of choice.