Ann Dermatol.  2009 May;21(2):174-177. 10.5021/ad.2009.21.2.174.

A Case of Membranous Lipodystrophy Observed in Lichen Amyloidosis

• Lee Y
• Ahn SY
• Ji JH
• Hong SP
• Bak H
• Lee SH
• Ahn SK

• KMID: 2219390
• DOI: http://doi.org/10.5021/ad.2009.21.2.174

Abstract

Membranous lipodystrophy is characterized by the presence of microcysts lined by amorphous, eosinophilic material with an arabesque appearance. We experienced a case of a 72-year-old man who had dark brownish, pruritic papules on the arms, legs, and back. Histopathologic examination of a biopsied lesion showed homogeneous, eosinophilic material in the papillary dermis, as well as membranous lipodystrophy. We report a case of membranous lipodystrophy observed in lichen amyloidosis.

Keyword

Lichen amyloidosis; Membranous lipodystrophy

MeSH Terms

Aged
Amyloidosis
Arm
Dermis
Eosinophils
Humans
Leg
Lichens
Lipodystrophy

Figure

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  Fig. 1 Multiple pruritic, dark brownish, hyperkeratotic papules on the arms (A), legs (B), and back (C).

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  Fig. 2 (A) Histopathology showing hyperkeratosis and irregular acanthosis of the epidermis (H&E, ×40) and (B) homogenous eosinophilic material in the papillary dermis (H&E, ×200). (C) Dilated and thickened blood vessels are surrounded by inflammatory cells (H&E, ×200), and (D) the lipomembranes have feathery projections into the fat lobules (H&E, ×400).

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