Korean J Dermatol.  1999 Jan;37(1):91-96.

Three Cases of Secondary Membranous Lipodystrophy

• Seo SL
• Kim MH
• Lim YS
• Choi HY
• Myung KB

Abstract

Membranous lipodystrophy is a peculiar type of fat necrosis, present in patients with various types of skin diseases. It is charaeterized by the presence of microcysts and macrocysts lined by amorphous eosinophilic material with a crenelated arabesque appearance and microgranules in the subcutis with massive fat necrosis. The eosinophilic lining and microgranules stain positively with periodic acid-Schiff, are resistant to diastase, and also stain with Sudan black B. We report three cases of subcutanous membranous lipodystrophy in patients with erythema induratum, posttraumatic panniculitis and morphea with typical clinical and histopathologic findings.

Keyword

Membranous lipodystrophy; Fat necrosis

MeSH Terms

Amylases
Eosinophils
Erythema Induratum
Fat Necrosis
Humans
Lipodystrophy*
Panniculitis
Scleroderma, Localized
Skin Diseases
Sudan
Amylases