J Korean Ophthalmol Soc.  2014 Sep;55(9):1307-1312. 10.3341/jkos.2014.55.9.1307.

The Effects of Lower Lid Laxity to the Response of Dry Eye Treatments

• Han JW
• Yim HB
• Lee NY

• KMID: 2217113
• DOI: http://doi.org/10.3341/jkos.2014.55.9.1307

Abstract

PURPOSE
To compare the response of dry eye treatment in patients divided by the degree of lower lid laxity.
METHODS
Thirty patients were classified into three groups - normal, moderate and severe, according to the degree of lower lid laxity. Tear break-up time (TBUT), Schirmer test (ST), ocular surface disease index (OSDI) scores and changes in OSDI score in each group were compared before and at 3 months after the treatment.
RESULTS
TBUT, ST and OSDI scores were not different among the three groups at baseline. TBUT improved to 6.60 +/- 1.43, 6.0 +/- 2.54 and 6.0 +/- 1.45 sec in normal, moderate and severe lower lid laxity group, respectively at 3 months after the treatment and no difference among the groups was found. ST scores did not increase after the treatment, while OSDI scores improved to 12.20 +/- 1.40, 16.10 +/- 4.63 and 20.80 +/- 4.52 in each group, respectively and they were significantly different (p = 0.029, 0.029, <0.001, respectively). The response to the dry eye treatment as assessed by changes in OSDI scores was poorer in patients in the severe lower lid laxity group (p = 0.019 vs. moderate laxity group, <0.01 vs. normal group).
CONCLUSIONS
As the degree of lower lid laxity increases, the response to dry eye treatment becomes poorer even when TBUT increases.

Keyword

Dry eye; Lower lid laxity; OSDI; Schirmer test; Snap-back test

MeSH Terms

Humans

Figure

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  Figure 1. Changes in tear break-up time (TBUT), before and at 3 months after the treatment in eyes grouped by the degree of lower lid laxity.

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  Figure 2. Changes in Schirmer test (ST) before and at 3 months after the treatment in eyes grouped by the degree of lower lid laxity.

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  Figure 3. Changes in ocular surface disease index (OSDI) scores before and at 3 months after the treatment in eyes grouped by the degree of lower lid laxity. *Mann Whitney test (significance level is p < 0.05).

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  Figure 4. Comparison of changes in ocular surface disease index (OSDI) scores between pretreatment and at 3 months after the treatment in eyes grouped by the degree of low er lid laxity. *Mann Whitney test (significance lev el is p < 0.05).

Reference

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