J Korean Ophthalmol Soc.  2013 Feb;54(2):289-295. 10.3341/jkos.2013.54.2.289.

Age-Related Differences of Spectral-Domain Optical Coherence Tomography Data in Koreans

• Suh JY
• Seo HR
• Rho SH

• KMID: 2216665
• DOI: http://doi.org/10.3341/jkos.2013.54.2.289

Abstract

PURPOSE
We evaluated the thickness of RNFL and optic nerve head parameters with age in normal eyes using Spectral-Domain Optical Coherence Tomography (SD-OCT).
METHODS
A total of 128 normal Korean volunteers in different age groups were recruited (age range, 20-70 years).
RESULTS
A significant negative correlation in average RNFL thickness with increasing age was found. The inferior areas (130.31 +/- 3.33 micrometer) were significantly thicker than other areas (superior area 119.05 +/- 2.12 micrometer, nasal area 71.80 +/- 0.57 micrometer, temporal area 77.72 +/- 0.16 micrometer). The average C/D ratios (mean 0.38 +/- 0.14) and vertical C/D ratios (mean 0.35 +/- 0.11) both showed significant increases with age, and the vertical C/D ratio correlation coefficient was higher (average C/D ratio r = 0.249, vertical C/D ratio r = 0.537). However, rim area, disc area, and cup volume were not correlated with age.
CONCLUSIONS
From these findings, we conclude that, in normal Koreans, the mean RNFL thickness decreases and the C/D ratio increases with age, with the increase in the vertical C/D ratio being greater.

Keyword

Optic disc parameter; Retinal nerve fiber layer thickness; Spectral-domain optical coherence tomography

MeSH Terms

Eye
Humans
Optic Disk
Tomography, Optical Coherence

Figure

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  Figure 1. The relationship between average cup/disc (C/D) area ratio and age. Average C/D area ratio increases with age significantly (p < 0.05).

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  Figure 2. The relationship between vertical cup/disc (C/D) area ratio and age. Vertical C/D ratio increases with age significantly (p < 0.05).

Reference

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