J Korean Ophthalmol Soc.  2012 Dec;53(12):1766-1771. 10.3341/jkos.2012.53.12.1766.

Short-Term Clinical Outcomes of Pterygium Treatment with Conjunctival Flap Advancement

Affiliations
  • 1Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea. jongsool@pusan.ac.kr

Abstract

PURPOSE
The present study reviewed the surgical outcomes of conjunctival flap advancement with pterygial tissue excision in primary and recurrent pterygium.
METHODS
In a retrospective survey of 169 eyes of 169 patients who underwent pterygial tissue excision and conjunctival flap advancement surgery, after a three-month follow-up minimum, history of pterygium surgery, surgical outcomes, recurrence rates, and complications were evaluated.
RESULTS
The study included 74 male and 95 female patients. The mean age was 56 +/- 11.93 years (range: 31-81 years). One hundred and forty eyes were considered as primary pterygium without history of surgery and 29 eyes were considered as recurrent pterygium. In the cases of primary pterygium, 139 eyes were treated after the surgery without recurrence (success rate: 99.2%) and one recurred case was localized to the sclera. Among the 29 eyes with recurrent pterygium, 26 eyes were treated without recurrence (success rate: 89.7%) and 3 recurred cases were localized to the sclera. There were no significant complications related to the surgical procedures.
CONCLUSIONS
Conjunctival flap advancement surgery with pterygial tissue excision was an effective method in primary and recurrent pterygium treatment and showed low recurrence and minimal complications.

Keyword

Conjunctival flap; Pterygium surgery; Recurrent pterygium

MeSH Terms

Eye
Female
Follow-Up Studies
Humans
Male
Pterygium
Recurrence
Retrospective Studies
Sclera

Figure

  • Figure 1 The surgical procedure of advancement conjunctival flap. (A) The pterygium head is dissected from cornea using blade knife, and the pterygium body including subconjunctival tissue is dissected using scissors. (B) Design of superior and inferior conjunctival flap. Surgical incision is made at the nasal and temporal side of sclera bed parallel to cornea limbus. (C) The conjunctival flap is advanced to cover the bare sclera. U-shaped conjunctiva-sclera-conjunctiva suturing was performed to conjoin upper and lower flaps. The center of the flap edge is sutured to the sclera. ×: conjunctiva-sclera-conjunctiva suture ∨: conjunctiva-conjunctiva suture.

  • Figure 2 Slit lamp photographs showing the clinical outcome of advancement conjunctival flap for primary pterygium. (A) Preoperatively, thickened, fibrovascular conjunctival tissues involved the limbus and cornea. Two weeks (B) and 3 months (C) after surgery, conjunctival chemosis and injection decreased.

  • Figure 3 Slit lamp photographs showing the clinical outcome after advancement conjunctival flap for recurred pterygium (G3). (A) Preoperatively, thickened, inflamed conjunctival tissues involved the limbus and cornea. Two weeks (B) and 3 months (C) after operation, there was no sign of recurrence.


Reference

1. Taylor HR, West S, Muñoz B, et al. The long-term effects of visible light on the eye. Arch Ophthalmol. 1992. 110:99–104.
2. Di Girolamo N, Chui J, Coroneo MT, Wakefield D. Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases. Prog Retin Eye Res. 2004. 23:195–228.
3. Reisman D, McFadden JW, Lu G. Loss of heterozygosity and p53 expression in Pterygium. Cancer Lett. 2004. 206:77–83.
4. Tan DT, Tang WY, Liu YP, et al. Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium. Br J Ophthalmol. 2000. 84:212–216.
5. Solomon A, Li DQ, Lee SB, Tseng SC. Regulation of collagenase, stromelysin, and urokinase-type plasminogen activator in primary pterygium body fibroblasts by inflammatory cytokines. Invest Ophthalmol Vis Sci. 2000. 41:2154–2163.
6. Ang LP, Chua JL, Tan DT. Current concepts and techniques in pterygium treatment. Curr Opin Ophthalmol. 2007. 18:308–313.
7. van den Brenk HAS. Results of prophylactic postoperative irradiation in 1,300 cases of pterygium. Am J Roentgenol. 1968. 103:723–733.
8. Tarr KH, Constable IJ. Late complications of pterygium treatment. Br J Ophthalmol. 1980. 64:496–505.
9. Rubinfeld RS, Pfister RR, Stein RM, et al. Serious complications of topical mitomycin-C after pterygium surgery. Ophthalmology. 1992. 99:1647–1654.
10. Kang BN. Postoperative recurrence rate of superior-inferior sliding conjunctival flap and mytomycin-C for the treatment of primary pterygium. J Korean Ophthalmol Soc. 1999. 40:721–727.
11. Prabhasawat P, Barton K, Burkett G, Tseng SC. Comparison of conjunctival autografts, amniotic membrane grafts, and primary closure for pterygium excision. Ophthalmology. 1997. 104:974–985.
12. Ehrlich D. The management of pterygium. Ophthalmic Surg. 1977. 8:23–30.
13. Youngson RM. Recurrence of pterygium after excision. Br J Ophthalmol. 1972. 56:120–125.
14. Koh YM, Kim JY, Ji NC. A Comparative study of recurrence rate in bilateral pterygium surgery : conjunctival autograft transplantation versus bare scleral techinque. J Korean Ophthalmol Soc. 2001. 42:1543–1548.
15. Kenyon KR, Wagoner MD, Hettinger ME. Conjunctival autograft transplantation for advanced and recurrent pterygium. Ophthalmology. 1985. 92:1461–1470.
16. Broadway DC, Grierson I, Hitchings RA. Local effects of previous conjunctival incisional surgery and the subsequent outcome of filtration surgery. Am J Ophthalmol. 1998. 125:805–818.
17. Sasaki K, Shishido A, Hosohata J, et al. Histological classification of pterygium. Jpn J Clin Ophthalmol. 1997. 51:1135–1138.
18. Tseng SCG, Chen JJY, Huang AJW, et al. Classification of conjunctival surgeries for corneal diseases based on stem cell concept. Ophthalmol Clin North Am. 1990.
19. Frau E, Labétoulle M, Lautier-Frau M, et al. Corneo-conjunctival autograft transplantation for pterygium surgery. Acta Ophthalmol Scand. 2004. 82:59–63.
20. Du Z, Jiang D, Nie A. [Limbal epithelial autograft transplantation for treatment of pterygium]. Zhonghua Yan Ke Za Zhi. 1998. 34:391–392.
21. Ahn DG, Auh SJ, Choi YS. The clinical results of limbal conjunctival autograft transplantation with intraoperative mitomycin C application for recurrent pterygia. J Korean Ophthalmol Soc. 1999. 40:2443–2449.
22. Syam PP, Eleftheriadis H, Liu CS. Inferior conjunctival autograft for primary pterygia. Ophthalmology. 2003. 110:806–810.
23. Oh TH, Choi KY, Yoon BJ. The effect of conjunctival autograft for recurrent pterygium. J Korean Ophthalmol Soc. 1994. 35:1335–1339.
24. Akura J, Kaneda S, Matsuura K, et al. Measures for preventing recurrence after pterygium surgery. Cornea. 2001. 20:703–707.
25. Alpay A, Uğurbaş SH, Erdoğan B, et al. Comparing techniques for pterygium surgery. Clin Ophthalmol. 2009. 3:69–74.
26. Cho JW, Chung SH, Seo KY, Kim EK. Conjunctival Mini-flap technique and conjunctival autotransplantation in pterygium surgery. J Korean Ophthalmol Soc. 2005. 46:1471–1477.
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