J Korean Ophthalmol Soc.  2015 Feb;56(2):304-308. 10.3341/jkos.2015.56.2.304.

A Case of Reverse Amblyopia of the Dominant Eye that was Refractory to Treatment

• Kim MS
• Kim WJ
• Kim MM

• KMID: 2216019
• DOI: http://doi.org/10.3341/jkos.2015.56.2.304

Abstract

PURPOSE
The treatment for reverse amblyopia is to discontinue occlusion therapy with most cases showing improvement of visual acuity in the dominant eye. Herein, we report a case of reverse amblyopia after monocular cataract surgery which was refractory to treatment and showed strabismus.
CASE SUMMARY
A 3-month-old female was diagnosed with congenital cataract in her left eye and underwent aspiration of lenses, posterior capsulectomy, and anterior vitrectomy. After the surgery, her mother performed strict 6:1 occlusion therapy on her right eye as prescribed. The best corrected visual acuity measured for the first time at the age of 32 months was 1.70 in the right eye and 0.52 in the left eye and the patient was referred to the Pediatric Ophthalmology clinic. At that time, eccentric fixation with slight exotropia was observed. With the diagnosis of reverse amblyopia in the right eye, the occlusion therapy was postponed for several months, however, visual acuity in the right eye did not recover after 4 months. After the age of 3 years, she was treated with left eye occlusion therapy, but the vision was still low and eccentric fixation was observed. At the age of 5 years she was continuously treated with left eye occlusion and the eccentric fixation improved, and at 6 years of age, a secondary intraocular lens implantation was performed. At 9 years of age, the patient underwent lateral rectus recession and medial rectus resection in the right eye for the treatment of exotropia.
CONCLUSIONS
In the case of monocular congenital cataract, occlusion therapy should be prescribed after surgical treatment. However, because reverse amblyopia which is refractory to treatment can occur, the fixation pattern should be monitored carefully and the occlusion duration controlled appropriately.

Keyword

Congenital cataract; Eccentric fixation; Exotropia; Occlusion therapy; Reverse amblyopia

MeSH Terms

Amblyopia*
Cataract
Diagnosis
Exotropia
Female
Humans
Infant
Lens Implantation, Intraocular
Mothers
Ophthalmology
Strabismus
Visual Acuity
Vitrectomy

Figure

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  Figure 1. The eccentric fixation on the right eye (A), and left eye fixation without correction (B).

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  Figure 2. The preoperative ocular alignment (A). Postoperative 1 month after the lateral rectus recession and medial rectus resection on the right eye (B).

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  Figure 3. At the age of 11 years, the color fundus photographs (A, C) and the spectral-domain optical coherence tomography (B, D) were normal in the both eyes.

Reference

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