J Korean Ophthalmol Soc.  2015 Aug;56(8):1242-1247. 10.3341/jkos.2015.56.8.1242.

Risk Factors and Clinical Manifestations of Ocular Hypertension after Primary Repair of Open Globe Injury

Affiliations
  • 1Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. exo70@naver.com

Abstract

PURPOSE
To investigate the risk factors and clinical manifestations of ocular hypertension (HTN) after repair of open globe injury (OGI).
METHODS
In a retrospective study of 284 patients who underwent primary repair of open globe injury at the day of trauma, best corrected visual acuity (BCVA) at the time of trauma and 6 months postoperatively, length of laceration, location of laceration and mean intraocular pressure (IOP) at 1 month after primary repair were analyzed. Presence of iris injury, lens injury, intraocular foreign body (IOFB) and vitreous hemorrhage (VH) were also analyzed. Ocular hypertension was defined as elevation of IOP greater than or equal to 21 mm Hg over 3 measurements.
RESULTS
Fourteen (4.93%) of 284 patients had ocular hypertension. BCVA (log MAR) at the time of trauma in the ocular HTN group was significantly worse than in the normal IOP group (2.43 +/- 1.04 and 1.76 +/- 1.30, respectively, p = 0.033). In the multivariate analysis, ocular HTN increased significantly with IOFB (p = 0.038; odds ratio [OR], 3.584; 95% confidence interval [CI], 1.075-11.941) and VH (p = 0.028; OR, 3.971; 95% CI, 1.157-13.624). BCVA increased significantly after repair in both groups and mean IOP was well controlled after medical therapy (9 eyes) or surgical treatment (5 eyes) in the ocular HTN group (28.1 +/- 4.7 and 15.8 +/- 3.8, respectively, p < 0.01).
CONCLUSIONS
Ocular HTN increased significantly with IOFB and VH at the time of trauma after repair of OGI and can be effectively treated by medication or surgical approach.

Keyword

Intraocular pressure; Ocular hypertension; Open globe injury

MeSH Terms

Foreign Bodies
Humans
Intraocular Pressure
Iris
Lacerations
Multivariate Analysis
Ocular Hypertension*
Odds Ratio
Retrospective Studies
Risk Factors*
Visual Acuity
Vitreous Hemorrhage

Reference

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