J Korean Ophthalmol Soc.  2016 Jan;57(1):14-19. 10.3341/jkos.2016.57.1.14.

Laser Iridotomy-Induced Bullous Keratopathy in Korea: Clinical Features and Comparison with Pseudophakic Bullous Keratopathy

• Choi SY
• Choi SI
• Lim SA
• Kim MS

• KMID: 2213829
• DOI: http://doi.org/10.3341/jkos.2016.57.1.14

Abstract

PURPOSE
To investigate the clinical features and prevalence of patients with laser iridotomy-induced bullous keratopathy in Korea.
METHODS
Using a retrospective study, the patients with laser iridotomy-induced bullous keratopathy who underwent penetrating keratoplasty were selected. We investigated the duration from iridotomy to corneal decompensation, preoperative anterior chamber depth, axial length, keratometry, and survival time of the grafted cornea. The data were compared with the data of patients with pseudophakic bullous keratopathy as controls.
RESULTS
Laser iridotomy-induced bullous keratopathy was found in 17 eyes, which represented 2.3% of penetrating keratoplasty cases (727) and 8.5% of bullous keratopathy cases (201), with a mean age of 66.9 years. The laser iridotomy-induced bullous keratopathy group showed a higher female ratio (15 out of 17), shorter mean axial length (22.09 +/- 0.79 mm) and anterior chamber depth (1.91 +/- 0.36 mm) than the control group (15 out of 50, 24.30 +/- 2.54 mm and 3.27 +/- 0.66 mm, respectively) with a statistical significance (p = 0.002, p < 0.001 and p < 0.001, respectively). Mean survival time of the grafted cornea was 39.9 +/- 8.6 months in the group of laser iridotomy-induced bullous keratopathy, which was shorter than the control group (47.8 +/- 3.1 months) without statistical significance (p = 0.47).
CONCLUSIONS
In Korea, laser iridotomy-induced bullous keratopathy shows non-negligible prevalence and should be further investigated.

Keyword

Bullous keratopathy; Laser iridotomy; Penetrating keratoplasty

MeSH Terms

Anterior Chamber
Cornea
Female
Humans
Keratoplasty, Penetrating
Korea*
Prevalence
Retrospective Studies
Survival Rate
Transplants

Figure

• 

  Figure 1. Clinical photograph of two patients with laser iridotomy-induced bullous keratopathy. Both eyes (A and B) are phakic and have iridotomy site on the superior-nasal side. Diffuse edematous cornea is noted which is consistent with bullous keratopathy.

• 

  Figure 2. Survival time analyzed by Kaplan-Meier curve. Mean survival time of the group of pseudophakic bullous ker-atopathy (47.8 months) is superior to that of the group of laser iridotomy-induced bullous keratopathy (39.9 months) without statistical significance by log-rank test ( p = 0.47).

Reference

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