J Korean Ophthalmol Soc.  2010 Jun;51(6):881-884. 10.3341/jkos.2010.51.6.881.

A Case of Solitary Fibrous Tumor of Orbit

• Kim EK
• Paik JS
• Yang SW

• KMID: 2213624
• DOI: http://doi.org/10.3341/jkos.2010.51.6.881

Abstract

PURPOSE
A Solitary fibrous tumor is a rare orbital neoplasm derived from mesenchymal cells. The neoplasm should be considered in differential diagnosis of any orbital tumor, and immunohistochemial analysis is important for correct diagnosis. The authors herein describe a case of a solitary fibrous tumor in addition to the findings of a literature review. Solitary fibrous tumors can develop from not only the lacrimal gland, but also orbital soft tissue. Until now, there has been no report of a solitary fibrous tumor arising from orbital soft tissue in Korea.
CASE SUMMARY
A 50-year-old man visited our clinic due to a slow progressing mass on the lateral side of the left eye for 1 year. The patient did not suffer from any discomfort or discharge from the mass. Slit lamp and other ocular examinations were unremarkable. Orbital MRI revealed a solid extra-conal enhanced mass that measured 13x11 mm adhering to the lateral wall of the left orbit. Total surgical excision was Performed under local anesthesia and tumor cells showed a strong and diffuse positivity for CD34 by immunohistochemistry. The findings were consistent with the diagnosis of orbital solitary tumor.
CONCLUSIONS
The orbital solitary tumor is rare, but it should be considered in the differential diagnosis of any orbital tumor.

Keyword

Orbital soft tissue; Solitary fibrous tumor

MeSH Terms

Anesthesia, Local
Diagnosis, Differential
Eye
Humans
Immunohistochemistry
Korea
Lacrimal Apparatus
Middle Aged
Orbit
Orbital Neoplasms
Solitary Fibrous Tumors

Figure

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  Figure 1. Preoperative external photographs of the fixed non-tender mass on the lateral side of the left lower eye-lid (black arrow) and lower lid entropion.

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  Figure 2. Orbital CT (coronal view) finding shows a 13 mm×11 mm-sized well-circumscribed mass with ho-mogenous enhancement at the left lower orbital area.

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  Figure 3. (A) The mass is removed by anterior orbitotomy. (B) Macroscopically the tumor mass displays 15 mm×12 mm×8 mm-sized reddish surface and hard-elastic consistency.

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  Figure 4. (A) Hematoxylin and eosin (H-E) stain shows spindle-shaped cells in variable arrangement (×100). (B) Immunohistochemical stain shows a strong and diffuse positivity for CD34 (×200).

Reference

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