J Korean Ophthalmol Soc.  2008 Aug;49(8):1283-1288. 10.3341/jkos.2008.49.8.1283.

Fibrin Glue for Conjunctival Closure in Pars Plana Vitrectomy

• Lee EK
• Kim JY

• KMID: 2211733
• DOI: http://doi.org/10.3341/jkos.2008.49.8.1283

Abstract

PURPOSE: To investigate the efficacy of fibrin glue for conjunctival closure in vitrectomy.
METHODS
Two hundred five eyes of 200 patients who underwent conjunctival closure for vitrectomy with a minimum follow-up period of six months were evlauated. Postopertive pain, foreign body sensation, tearing, subconjunctival hemorrhage, surgery time and complication were evaluated prospectively in 105 eyes of 100 patients undergoing surgery with fibrin glue, and in 100 eyes of 100 patients undergoing surgery with sutures.
RESULTS
One day postoperatively, pain scores (p< 0.05), foreign body sensation (p< 0.05), tearing (p< 0.05), and subconjunctival hemorrhage (p< 0.05) were significantly lower in the fibrin glue group than in the suture group. One week postoperatively, the scores of foreign body sensation (p< 0.05), tearing (p< 0.05), subconjunctival hemorrhage (p< 0.05) were significantly lower in the fibrin glue group than in the suture group. The mean surgery time in the fibrin glue group (2.2+/-0.5 minutes) was significantly shorter than that in the sutures group (7.4+/-0.6 minutes) (p< 0.05).
CONCLUSIONS
The Use of fibrin glue for conjunctival closure in vitrectomy can reduce postoperative discomfort and surgical time. It is especially useful for a second operation or for cases with a thin, atrophic conjunctiva.

Keyword

Conjunctival closure; Fibrin glue; Vitrectomy

MeSH Terms

Conjunctiva
Eye
Fibrin
Fibrin Tissue Adhesive
Follow-Up Studies
Foreign Bodies
Hemorrhage
Humans
Operative Time
Prospective Studies
Sensation
Sutures
Vitrectomy
Fibrin
Fibrin Tissue Adhesive

Figure

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  Figure 1. Clinical appearance of 2 eyes postoperative 3 day: conjunctival closure with Greenplast® (A, B) and with 8-0 Vicryl (C, D).

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  Figure 2. Day 1 postoperative signs and symptoms (average score) in the patients treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

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  Figure 3. Week 1 postoperative signs and symptoms (average score) in the patients treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

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  Figure 4. Day 1 postoperative signs and symptoms (average score) in the patients over 70 years old those had atrophic, thin conjunctiva treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

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  Figure 5. Week 1 postoperative signs and symptoms (average score) in the patients over 70 years old those had atrophic, thin conjunctiva treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

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  Figure 6. Day 1 postoperative signs and symptoms (average score) in the patients those had second operation treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

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  Figure 7. Week 1 postoperative signs and symptoms (average score) in the patients those had second operation treated with glue compared with those treated with suture (* p<0.05, Mann-Whitney U test).

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  Figure 8. Operative time in the patients treated with glue compared with those treated with suture (* p<0.05, Mann- Whitney U test).

Reference

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