J Korean Ophthalmol Soc.  2008 May;49(5):835-839. 10.3341/jkos.2008.49.5.835.

A Case of Anterior Fibrovascular Membrane After Intraocular Lens Implantation in Congenital Aniridia

• Lee KS
• Moon JW
• Park JW
• Choi JH

• KMID: 2211716
• DOI: http://doi.org/10.3341/jkos.2008.49.5.835

Abstract

PURPOSE: To report a case of an anterior fibrovascular membrane following cataract extraction and intraocular lens implantation in a patient with congenital aniridia.
CASE SUMMARY
A 13-year-old girl presented with congenital aniridia and cataracts in both eyes. She underwent cataract extraction by phacoemulcification with intraocular lens implantation. Six months after cataract surgery, a progressive anterior chamber fibrovascular membrane was noted in both intraocular lens and rudimentary iris. Surgical excision of the fibrovascular membrane was performed, but there was recurrence after five weeks in both eyes. Subsequent surgical intervention on both eyes involved intraocular lens explantation combined with membranectomy to prevent recurrence and phthisis. Surgical findings indicated that the fibrovascular membrane involved the retrolenticular space, and histopathological evidence indicated that the extensive fibrotic tissue originated from the root of the rudimentary iris.
CONCLUSIONS
Patients with congenital aniridia should be monitored carefully for the development of intraocular fibrosis after intraocular lens implantation. If a fibrovascular membrane is noted, early surgical intervention is recommended, and the explantation of the intraocular lens should be considered during surgical intervention to prevent recurrence and complications.

Keyword

Anterior fibrovascular membrane; Congenital aniridia; Intraocular lens

MeSH Terms

Adolescent
Aniridia
Anterior Chamber
Cataract
Cataract Extraction
Eye
Fibrosis
Humans
Iris
Lens Implantation, Intraocular
Lenses, Intraocular
Membranes
Recurrence

Figure

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  Figure 1. (A) Preoperative microscopic findings after intraocular lens implantation. (B) Progressive formation of fibrovascular membrane (F) with extension of the membrane anteriorly in the anterior chamber. C = cornea: I = black-diaphragm intraocular lens. (C) Intraocular lens (I) explantation combined with fibrovascular membrane removal. (D) Microscopic findings after fibrovascular membrane removal.

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  Figure 2. Light microscopy of fibrous membrane shows dense hypocellular fibrous membrane (F) with mild vascularization. H = lens haptic imprint; I = iris root. (Hematoxylin and eosin stain; original magnification, (A) ×20; (B) ×40).

Reference

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