J Korean Ophthalmol Soc.  2008 Jan;49(1):104-110. 10.3341/jkos.2008.1.104.

Multifocal Electroretinogram before and after Epiretinal Membrane Surgery

• Kang JH
• Choi ES
• Yoon JM
• Yoon HS

• KMID: 2211189
• DOI: http://doi.org/10.3341/jkos.2008.1.104

Abstract

PURPOSE: To assess macular function before and after vitrectomy and membrane removal in epiretinal membranes by means of multifocal electroretinogram (mfERG).
METHODS
The mfERGs (RETIscan(R), Roland, Germany) of 28 consecutive patients (28 eyes) with idiopathic epiretinal membranes were recorded before epiretinal membrane surgery and 3 to 6 months after surgery. The average retinal response density and implicit time of each local response were estimated as anatomic macular areas corresponding roughly to 5 rings. Preoperative and postoperative responses of mfERG were compared. The correlation of the change of retinal response density and postoperative macular configuration on optical coherent tomography (OCT) was statistically analyzed.
RESULTS
The postoperative value of P1 amplitude and implicit time were not statistically correlated with the preoperative value (p>0.05). There were no significant correlations between the changes of rings 1 and 2 with regard to the retinal response density of the mfERGs and visual acuity. There was no significant correlation between the change of retinal response density and postoperative macular configuration according to OCT.
CONCLUSIONS
The use of mfERGs does not seem useful for predicting clinical prognosis after epiretinal membrane surgery. Further studies of influence of internal limiting membrane removal on mfERG response should be conducted.

Keyword

Epiretinal membrane; Macular function; Multifocal electroretinogram

MeSH Terms

Epiretinal Membrane
Humans
Membranes
Prognosis
Retinaldehyde
Visual Acuity
Vitrectomy
Retinaldehyde

Figure

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  Figure 1. Preoperative color fundus photograph showed thin macular epiretinal membrane (A). Internal limiting membrane was peeled off using a microforceps at an area of approximately 3 disc diameters surrounding the fovea (B).

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  Figure 2. Relationship between preoperative and postoperative (A) amplitude of the ring 1, (B) amplitude of the ring 2. There are significant correlation between the two parameters (p<0.05).

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  Figure 3. Preoperatvie (A) and postoperative (B) OCT (optical coherence tomography) and mfERG (multifocal electroretinogram) findings of a 56-year-old male with epiretinal membrane.

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  Figure 4. Number of patients according to postoperative OCT findings of the macula.

Reference

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