J Korean Ophthalmol Soc.  2008 Jan;49(1):91-97. 10.3341/jkos.2008.49.1.91.

The Intraocular Pressure Rise Secondary to Subtenon's Injection of Triamcinolone After Intravitreal Injection

• Kim WJ
• Park YH

• KMID: 2211187
• DOI: http://doi.org/10.3341/jkos.2008.49.1.91

Abstract

PURPOSE: To evaluate the safety of posterior subtenon's injection of triamcinolone acetonide (PSTA) after intravitreal triamcinolone acetonide injection (IVTA).
METHODS
We reviewed the charts of 34 patients who had previously treated with IVTA. Patients were categorized as steroid responder or non-responder. Responders were defined as having a relative intraocular pressure increase of 5 mmHg and absolute intraocular pressure greater than 24 mmHg. Relative risk of intraocular pressure was prospectively evaluated after PSTA. RESULT: Eighteen eyes were categorized as steroid responders after IVTA injection and sixteen eyes were categorized as non-responders. For the actual amount of increase in the intraocular pressures, the steroid responder group (39%) was shown to be statistically higher than the non-responder group (6%) (P=0.044). However, the mean pressure values did not show a significant difference (P>0.05). Only one eye required the use of glaucoma medications and the intraocular pressure remained normal after treatment.
CONCLUSIONS
PSTA is a relatively safe treatment method after IVTA injection regardless of steroid responsiveness.

Keyword

Intraocular pressure; Subtenon injection; Triamcinolone acetonide

MeSH Terms

Eye
Glaucoma
Humans
Intraocular Pressure
Intravitreal Injections
Prospective Studies
Triamcinolone
Triamcinolone Acetonide
Triamcinolone
Triamcinolone Acetonide

Figure

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  Figure 1. Comparison of mean intraocular pressure after intravitreal triamcinolone acetonide injection between responders and non-responders.

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  Figure 2. Comparison of mean intraocular pressure after posterior subtenon’s injection of triamcinolone acetonide between responders and non-responders.

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  Figure 3. Kaplan-Meier survival curves comparing probability of intraocular pressure elevation between steroid responders and non-responders after posterior subtenon’s injection of triamcinolone acetonide (P=0.034 Kaplan-Meier analysis).

Reference

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