J Korean Ophthalmol Soc.  2007 Jan;48(1):97-102.

Intraocular Pressure Change After Secondary Intravitreal Triamcinolone Acetonide Injection

• Lee JM
• Kim SJ
• Yi KY
• Kim HK

Abstract

PURPOSE: To evaluate the change of intraocular pressure (IOP) after first and second injection of intravitreal triamcinolone acetonide for the treatment of macular edema and the factors that influence these changes.
METHODS
A prospective, non-comparative study was performed in 41 eyes at Kangnam Sacred Heart Hospital from October 2003 to November 2005. All of the patients received injection of intravitreal triamcinolone acetonide (4 mg) twice. The IOPs before and after triamcinolone injection were measured with non-contact tonometer and Goldmann applanation tonometer.
RESULTS
Mean IOP after the first and second injections were elevated from the day after injection and peaked after 3 months. Younger age (p=0.042), male (p=0.050) and the history of IOP elevation after first injection (p=0.004) were a statistically significant predictive factor for IOP elevation after second injection. Younger age (p=0.000) and male (p=0.010) were a significant predictive factor for IOP elevation after first and second injection.
CONCLUSIONS
Clinicians should consider checking IOP especially for the patients who with the history of IOP elevation after first injection, male and relatively younger age.

Keyword

Intraocular pressure; Male; Secondary intravitreal triamcinolone acetonide injection; Younger age

MeSH Terms

Heart
Humans
Intraocular Pressure*
Macular Edema
Male
Prospective Studies
Triamcinolone Acetonide*
Triamcinolone*
Triamcinolone
Triamcinolone Acetonide