J Korean Ophthalmol Soc.  2007 Jan;48(1):162-166.

Anterior Fibroblastic Proliferation of Lens Epithelial Cells in Acrylic Intraocular Lens

• Choi GW
• Hwang YH
• Moon SW
• Kim JH

Abstract

PURPOSE: To report upon two cases of anterior capsule opacification (ACO) proliferating into the pupillary region of the anterior surface of a single piece acrylic AcrySof(R) intraocular lens (IOL) (SA60AT, Alcon Laboratories, Inc., USA). The surgical removal of the ACO was also reported.
METHODS
An 80-year-old woman and a 75-year-old woman underwent phacoemulsification with implantation of a single piece foldable AcrySof(R) IOL in the posterior capsular bag. ACO proliferating from the opposite sides of the IOL along the central axis were found three months after surgery. To recover visual acuity in the 80-year-old woman's eye, ACO was surgically removed with a Sinskey hook and irrigation and aspiration system.
RESULTS
The patient's visual acuity was recovered after surgical removal of the ACO. Histopathologic findings of the removed tissues revealed fibroblastic proliferation of lens epithelial cells. The ACO in 75-year-old woman's eye was not treated, as it was not associated with a visual disturbance.
CONCLUSIONS
In eyes containing an AcrySof(R) IOL, clinically significant ACO proliferation into the pupillary region along the central axis can occur. Surgical removal can be beneficial for recovery of visual acuity.

Keyword

AcrySof(R) intraocular lens; Anterior capsule opacification

MeSH Terms

Aged
Aged, 80 and over
Axis, Cervical Vertebra
Capsule Opacification
Epithelial Cells*
Female
Fibroblasts*
Humans
Lenses, Intraocular*
Phacoemulsification
Visual Acuity