J Korean Ophthalmol Soc.
2007 Jan;48(1):7-12.
The Clinical Effect of Amniotic Membrane Transplantation for Various Ocular Surface Diseases
- Affiliations
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- 1Department of Ophthalmology, Chonbuk National University, College of Medicine, Jeonju, Korea. eyeprotector@hanmail.net
Abstract
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PURPOSE: To describe the clinical outcome of amniotic membrane transplantation(AMT) for various ocular surface diseases.
METHODS
We reviewed the medical records of 52 eyes from 46 patients which had underwent AMT for various ocular surface diseases. We scored each eyes from 0 to 4 for subjective symptoms (symptom score) and epithelial healing (epithelial grade) at three months after AMT. The clinical score was calculated as the symptom score time the epithelial grade.
RESULTS
The mean clinical score among all ocular surface disease was 10.41+/-4.26. The mean clinical scores for each disease are as follows: 7.71+/-3.56 for corneal ulcers, 14.43+/-3.1 for persistent epithelial defects, 12.83+/-2.71 for exposure keratitis, 12.86+/-3.18 for herpes keratitis, 5.85+/-2.5 for bullous keratopathy, 10.53+/-4.27 for chemical corneal burns and 16.0+/-0.0 for shield ulcers. Subjective symptoms subsides and epithelial healing progressed in all patients treated by AMT. No complications occurred.
CONCLUSIONS
AMT is an effective method for treating various ocular surface diseases, because AMT improves the subjective symptoms of patients and promotes the healing of epithelial lesions.
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