J Korean Ophthalmol Soc.  2006 Dec;47(12):1981-1986.

The Comparison of Intraocular Pressure Elevation after Intravitreal Injection of Different Concentration of Triamcinolone Acetonide

• Kim JM
• Kim HK
• Shon YH

Abstract

PURPOSE: The purpose of this study was to compare the effects of intravitreal injections of 4 mg or 8 mg triamcinolone acetonide(TA) on intraocular pressure (IOP) in macular edema.
METHODS
This was a retrospective study conducted by reviewing follow-up records for the eyes of 60 patients with macular edema 6 months receiving a intravitreal TA injection. Two groups, A and B, who had received TA injections of either 4 or 8 mg, respectively, were compared.
RESULTS
The average pre-injection IOP for group A was 12.8+/-2.6 mmHg, and the average post-injection IOP at 1 day, 1 week, 1 month, 3 months, and 6 months was 15.0+/-2.7, 14.6+/-3.2, 15.3+/-3.5, 15.8+/-4.0, and 14.4+/-2.8 mmHg, respectively. The average pre-injection IOP for group B was 12.5+/-2.4 mmHg, and the average post-injection IOP at 1 day, 1 week, 1 month, 3 months, and 6 months was 14.9+/-2.9, 14.3+/-3.0, 14.7+/-3.2, 15.2+/-4.4, and 14.5+/-4.5 mmHg, respectively. The difference in IOP elevation between the two groups was not statistically significant (p>0.05).
CONCLUSIONS
There was no statistically significant difference between a 4 mg or 8 mg intravitreal TA injection with respect to IOP elevation.

Keyword

Intraocular pressure; Intravitreal injection; Triamcinolone acetonide

MeSH Terms

Follow-Up Studies
Humans
Intraocular Pressure*
Intravitreal Injections*
Macular Edema
Retrospective Studies
Triamcinolone Acetonide*
Triamcinolone*
Triamcinolone
Triamcinolone Acetonide