J Korean Pediatr Soc.  1981 May;24(5):485-491.

Two Cases of IgA Nephropathy

• Lee HJ
• Kim WS
• Ahn DH
• Sohn KC
• Lee HS

Abstract

Two cases of IgA nephropathy in an 11-year-old girl(Case I) and a 10-year-old boy(Case II) were presented. Case I, an 11-year-old schoolgirl, had recurrent painless hematuria of 6-month duration which began with URI symptoms at the onset. No edema was noted and urine volume was sufficient throughout the course. Mild proteinuria had been noted from time to time. Blood pressure was 140/90mmHg on admission but dropped soon to normal. Percutaneous renal biop-sy revealed proliferative focal glomerulosclerosis on light microscopy, IgA(+++) deposition in mesangium and subendothelium on immunofluorescent study, and election dense deposit in the mesangium on electron microscopy. Case II, a 10-year-old schoolboy, had suffered from symptomless hematuria of 3-month duration. The onset developed with skin infection, the 2nd relapse with otitis media and the 3rd with URI like symptoms. Other lab, findings were all within normal limit. Renal biopsy revealed minor change with segmental focal glomerulosclerosis on light microscopy, mesangial deposition of IgA(+++) & C3(+) on immunofluorescent study, and electron lense deposit in the mesangium on electron microscopy.

Keyword

Recurrent hematuria; focal glomerulonephritis; IgA nephropathy

MeSH Terms

Biopsy
Blood Pressure
Child
Edema
Glomerulonephritis, IGA*
Glomerulosclerosis, Focal Segmental
Hematuria
Humans
Immunoglobulin A*
Microscopy
Microscopy, Electron
Otitis Media
Proteinuria
Recurrence
Skin
Immunoglobulin A