J Korean Pediatr Soc.  1994 May;37(5):701-706.

A Case of Brain Damage in Surviving Monozygotic Twin After Intrauterine Death of Co-Twin

Abstract

Various anatomical defects have been described in the surviving twin who had a stillborn, macerated monozygotic co-twin with Disseminated Intravascular Coargulation. The etiology is thought to be placental transfer of emboli or thromboplastic material through placental vascular anastomoses. We experienced a case of monozygotic twin with deceased co-twin at 30 weeks of gestation and confirmed to have antenatal periventricular germinal matrix and intraventricular hemorrhage, multicystic periventricular leukomalacia and diffuse encephalomalacia by neurosonography on first day of life despite of no clinical evidence of brain damage. The pathologic findings of placenta revealed infarct with massive fibrin deposition. A brief review of related literature is presented.


MeSH Terms

Brain*
Encephalomalacia
Fibrin
Hemorrhage
Humans
Infant, Newborn
Leukomalacia, Periventricular
Placenta
Pregnancy
Twins
Twins, Monozygotic*
Fibrin
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