J Korean Ophthalmol Soc.  2006 Feb;47(2):235-242.

Neovascularizations Associated with Large Serous Retinal Pigment Epithelial Detachment: Classification According to the Angiographic Features

• Park YH
• Lee WK

Abstract

PURPOSE: To differentiate serous pigment epithelial detachment (PED) according to angiographic features in elderly Korean patients.
METHODS
The fluorescein and indocyanine green angiograms of 72 eyes of 67 consecutive patients with a serous PED of at least 1 disc diameter were evaluated retrospectively
RESULTS
Polypoidal choroidal vasculopathy (PCV) and typical choroidal neovascularization (CNV) associated with PEDs were identified in 18 eyes (25%) and 19 eyes (26.4%), respectively. In 10 eyes (13.9%), it could not be determined whether the exact type of neovascularzation was PCV or CNV. Pure serous PEDs were identified in 7 eyes (10%). The remaining 18 eyes (25%) of 13 patients were classified as retinal angiomatous proliferation (RAP) associated with PED, based on the angiographic findings of anastomosis of the retinal vasculature with neovascular lesion, as well as clinical features such as diffuse soft drusen, extrafoveal location, preretinal or superficial retinal hemorrhage, and bilateral tendency.
CONCLUSIONS
In Asian patients with neovascularized, age-related macular degeneration (AMD), the incidence of PCV is known to be high, whereas the incidence of RAP is very low. However, the results of this study suggest that RAP is as common as PCV and CNV in a subset group of neovascularized AMD that is accompanied by serous PED.

Keyword

Angiographic features; Choroidal neovascularization; Polypoidal choroidal vasculopathy; Retinal angiomatous proliferation

MeSH Terms

Aged
Asian Continental Ancestry Group
Choroid
Choroidal Neovascularization
Classification*
Fluorescein
Humans
Incidence
Indocyanine Green
Macular Degeneration
Retinal Detachment*
Retinal Hemorrhage
Retinaldehyde*
Retrospective Studies
Fluorescein
Indocyanine Green
Retinaldehyde