J Korean Pediatr Soc.  1996 Mar;39(3):423-430.

A Case of Nonfamilial Generalized Gastrointestinal Juvenile Polyposis with Pancytopenia

Affiliations
  • 1Department of Pediatrics, Presbyterian Medical Center, Chonju, Korea.
  • 2Department of Clinical Pathology, Presbyterian Medical Center, Chonju, Korea.

Abstract

In contrast to the child with a solitary juvenile polyp, generalized gastrointestinal juvenile polyposis have a much different clinical course. In generalized juvenile polyposis blood loss can be considerable and iron-deficiency anemia is a common observation. Although it is usually regarded as a benign condition, juvenile polyposis may predispose to cancer of the gastrointestinal tract. We experienced a case of nonfamilial generalized gastrointestinal juvenile polyposis with pancytopenia in a 15 year-old male patient who had hospitalized because of intermittent rectal bleeding with anemia for three years. Histological examination of polyps from affected patient revealed a spectrum of change from juvenile polyps, to juvenile polyps with adenomatous changes. Subtotal colectomy, rectal mucosectomy, and endorectal pull-through procedure were successfully performed. No complication has occured since the discharge. A brief review of related literatures is also presented.

Keyword

Juvenile poluposis; GI tract; Pancytopenia

MeSH Terms

Adolescent
Anemia
Anemia, Iron-Deficiency
Child
Colectomy
Gastrointestinal Neoplasms
Gastrointestinal Tract
Hemorrhage
Humans
Male
Pancytopenia*
Polyps
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