J Korean Ophthalmol Soc.  2005 Aug;46(8):1361-1367.

The Outcomes After Indocyanine Green-assisted Peeling of the Internal Limiting Membrane in Macular Hole Surgery

• Hahm IR
• Tae KS
• Cho SW
• Lee TG
• Kim SH
• Kim JW
• Lee JH

Abstract

PURPOSE
To investigate whether indocyanine green (ICG) staining of the internal limiting membrane (ILM) improves surgical and visual outcomes in macular hole surgery. METHODS: Three consecutive groups of patients with stage 3 and stage 4 macular hole underwent standard vitrectomy. Group I (45 eyes) underwent an adjunctive peeling of ILM stained with intravitreal application of 0.1 ml of 0.5% ICG dye, group II (23 eyes) an adjunctive ILM peeling without use of ICG dye, and group III (23 eyes) no adjunctive technique. Postoperative anatomic closure rates of the hole and the logarithm of the minimal angle of resolution (logMAR) visual acuity improvement were compared among the groups. RESULTS: The mean age was 61 years, and the mean follow-up period was 11 months. The rate of macular hole closure, as determined by optical coherence topography was 70% in group I, 61% in group II, and 61% in group III, and the difference were not statistically significant (p=0.726). The differences between preoperative and postoperative logMAR visual acuities among the three groups were not statistically significant (p=0.898). CONCLUSIONS: Intravitreal ICG-assisted ILM peeling did not improve anatomic outcomes in macular hole surgery. (Ed-confirm, something appears to be missing here)

Keyword

Indocyanine green; Internal limiting membrane; Macular hole surgery

MeSH Terms

Follow-Up Studies
Humans
Indocyanine Green
Membranes*
Retinal Perforations*
Visual Acuity
Vitrectomy
Indocyanine Green