J Korean Pediatr Soc.
2000 Sep;43(9):1241-1247.
A Study of Endoscopic Variceal Ligation of under 6-Year-Old Aged Children with
Esophageal Varices
Abstract
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PURPOSE: Endoscopic variceal sclerotherapy(EVS) has been considered the mainstay therapy for
bleeding esophageal varices in adults. However, recent data have shown that endoscopic
variceal ligation is just as efficacious and has fewer complications than EVS. Although there
are many reports concerning EVL in adults, only a few studies have been done of children.
METHODS
We performed EVL in 9 children under 6 years of age(mear age, 2.5 year) with
esophageal varices. Outcome was assessed with respect to survival, rebleeding, and
complications.
RESULTS
The causes of portal hypertension were 3 cases of congenital hepatic fibrosis,
3 cases of biliary atresia, 2 cases of portal vein thrornbosis, and one case of portal vein
fibromuscular dysplasia. The age at diagnosis ranged from 10 months to 6 years. The patients
underwent a mean of 2.6+/- 0.7 sessions of EVL(ranging from two to four). The numbers of bands
per person were 5.6+/-1.8, and the numbers of bands per session were 2.2+/-1.0 Two complications
of esophageal rebleeding were noted, and none of the cases experienced symptoms of esophageal
stenosis, nor gastroesophageal reflux.
CONCLUSION
EVL is safe and effective in controlling variceal hemorrhage in children with
portal hypertension, regardless of etiology. The cornplication rate is low and EVL is an
acceptable and perhaps preferable altemative to EVS in children with esophageal varices. But
regular periodic examination for recurrence of varices after eradication should be required.