J Korean Soc Magn Reson Med.  2010 Dec;14(2):121-125. 10.13104/jksmrm.2010.14.2.121.

Clinical Experience of 3T Breast MRI in Detecting the Additional Lesions in Breast Cancer Patients

• Lee JH
• Kim SH
• Kang BJ
• Choi JJ
• Lee AW

• KMID: 2206909
• DOI: http://doi.org/10.13104/jksmrm.2010.14.2.121

Abstract

PURPOSE
The purpose of this study was to evaluate the diagnostic accuracy of 3.0-T breast MRI for detecting additional breast cancer soon after the initial diagnosis of breast cancer.
MATERIALS AND METHODS
From March to June 2009, 101 patients recently diagnosed breast cancer underwent breast MRI and surgery. Parameters analyzed on MRI were total extent of tumor, suspicious findings of multifocal, multicentric, or contralateral cancer. The diagnosis of MRI-detected cancer was confirmed by means of biopsy or surgical specimen evaluation after the localization.
RESULTS
MRI showed 37 additional suspicious findings in 34 patients. Twenty nine findings were true-positive (29/37, 78.4%), including 16 cases of multifocality, 11 cases of multicentricity and 2 cases of contralateral cancer. Among these cancers, 13 (44.8%) were ductal carcinoma in situ (DCIS) and 16 (55.1%) were infiltrating cancer. Eight findings were false-positive (8/37, 21.6%) including 6 cases of benign disease and 2 cases of high-risk lesions.
CONCLUSION
In women with recently diagnosed breast cancer, 3.0-T MR imaging showed additional suspicious findings in 33.7%. The sensitivity and specificity for detecting additional breast cancer was 100% and 89.3%, respectively.

Keyword

Magnetic resonance imaging; 3.0 Tesla; Breast; Breast cancer

MeSH Terms

Biopsy
Breast
Breast Neoplasms
Carcinoma, Intraductal, Noninfiltrating
Female
Humans
Magnetic Resonance Imaging
Sensitivity and Specificity

Figure

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  Fig. 1 35-year-old woman with invasive ductal cancer and true positive multifocal malignancies. 3D MIP image shows an index mass (arrow) and two multifocal daughter nodules (arrowheads) at upper outer quadrant of right breast.

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  Fig. 2 53-year-old woman with invasive ductal cancer and true positive multicentric malignancies. Axial subtraction image shows an index mass (arrow) at upper inner quadrant of left breast. Also detected multifocal and multicentric malignancies (arrowheads) are noted at left upper breast.

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  Fig. 3 63-year-old woman with invasive ductal cancer and true positive contralateral malignancy. Axial subtraction image shows an index mass at right breast and an irregular spiculated homogeneously enhancing mass at left breast.

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