J Korean Ophthalmol Soc.  2003 Sep;44(9):2184-2190.

Atypical Vogt-Koyanagi-Harada Syndrome in a 7-Year-Old Boy

• Oh J
• Oh IK
• Huh K

Abstract

PURPOSE
Vogt-Koyanagi-Harada syndrome is more common in adults than in children. We report a atypical case of Vogt-Koyanagi-Harada syndrome like white dot syndromes in a 7-year-old child. METHODS: A 7-year-old child visited with complaints of decreased binocular visual acuity. Under ophthalmologic examination, anterior uveitis and optic neuropathy were found. But there was no other retinal lesion. After high-dose intravenous corticosteroids pulse therapy, yellow pigment lesions like white dot syndromes developed in peripheral retina and enlarged without serous retinal detachment.
RESULTS
In 5 months after high-dose intravenous corticosteroids pulse therapy, anterior inflammation was decreased and visual acuity was 0.8 in both eyes. But depigmented retinal lesions were increased and sunset glow occurred. Alopecia and poliosis of hair were found. Human leukocyte antigen typings revealed HLA-DR4 antigen.

Keyword

Children; Vogt-Koyanagi-Harada syndrome; White dot syndrome

MeSH Terms

Adrenal Cortex Hormones
Adult
Alopecia
Child*
Hair
HLA-DR4 Antigen
Humans
Inflammation
Leukocytes
Male*
Optic Nerve Diseases
Retina
Retinal Detachment
Retinaldehyde
Telescopes
Uveitis, Anterior
Uveomeningoencephalitic Syndrome*
Visual Acuity
Adrenal Cortex Hormones
HLA-DR4 Antigen
Retinaldehyde