J Korean Ophthalmol Soc.  2000 Apr;41(4):1023-1027.

Treatment of Late Bleb Leak with Human Amniotic Membrane Transplantation

Affiliations
  • 1Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Late bleb leak after trabeculectomy is a serious and intractable complication and its frequency is increasing as antimetabolites are used in the surgery. Various modalities have been challenged in the treatment of late bleb leak but the results have not been satisfactory.Amniotic membrane is avascular tissue with thick basement membrane and rich stroma, and it can modulate wound.As it does not express HLA, it doesn t induce graft rejection. With the use of these characteristics of amniotic membrane, we report a case in which late bleb leak after trabeculectomy with MMC was successfully treated with amniotic membrane transplantation maintaining bleb function.

Keyword

Late bleb leak; Amniotic membrane transplantation; MMC; Trabeculectomy

MeSH Terms

Amnion*
Antimetabolites
Basement Membrane
Blister*
Graft Rejection
Humans*
Membranes
Trabeculectomy
Antimetabolites
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