J Korean Ophthalmol Soc.  1999 Mar;40(3):824-828.

Expression of Strabismus in Monozygotic Twins

Affiliations
  • 1Department of Ophthalmology, Yeungnam University College of Medicine.

Abstract

We have studied the concordance of strabismus in monozygotic twins to determine the influence of genetic inheritance in expression of strabismus. We examined 21 pairs of monozygotic twins(32 strabismic patients of 42). The average age was 5.5 years(2 months-23 years) at their first visit. Out of 21 pairs of monozygotic twins, 11 pairs were concordant(52%) in type of strbismus: 6 pairs in intermittent exotropia, 2 pairs in infantile estropia, and 3 pairs in partially accommodative esotropia. Not a single pair of twins were concordant in accommodative esotropia, dissociated vertical deviation, or superior oblique palsy. This study suggests that expression of strabismus in monozygotic twins may be discordant and that it is not determined merely by genetic inheritance, but also by various other factors. And those conceordant pairs in type results, and recurrence.

Keyword

Monozygotic twins; Strabismus

MeSH Terms

Esotropia
Exotropia
Humans
Paralysis
Recurrence
Strabismus*
Twins, Monozygotic*
Wills
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