J Korean Ophthalmol Soc.  1986 Aug;27(4):537-543.

Early Postoperative IOP Change Following Extracapsular Cataract Extraction with Posterior Chamber Implaratation and the Effect of Prophylactic Acetazolamide on Postoperative IOP

• Lee SW
• Kim MS
• Kim JH

Abstract

Twenty eight patients(30 eyes) undergoing extracapsular cataract extraction and posterior chamber lens insertion with Healon were studied for intraocular pressure. The patients were divided into experimental group(15 patients, 15 eyes) which received acetazolamide and control group (13 patients, 15 eyes) which received no acetazolamide. The remained Healon(R) in anterior chamber was removed with I and A system at the end of the procedure. Intraocular pressure was measured preoperatively and 3, 6, 12, 24, 48, 72 hours and 6 days after operation. The results were as follows: 1. The intraocular pressure at 3 hours of control group and treated group was 16.0 +/- 5.0mmHg(2.6% increase) and 17.0 +/- 5.1mmHg(4.3% increase) respectively. But it was not significant statistically. 2. The intraocular pressure at 6 hours of control group and treated group was 16.4 +/- 5.9mmHg(5.1% increase) and 14.1 +/- 3.9mmHg(13.5% decrease) respectively. The increased intraocular pressure was not significant statistically. 3. The intraocular pressure after 12 hours was significantly lowered than preoperative intraocular pressure in two groups(p<0.05). 4. The intraocular pressure was above 23mmHg in 3 cases(20%) of control group and in 1 case(6.7%) of treated group. Highest intraocular pressure was 28mmHg in each group. 5. The differences between two groups at each time was not significant statistically. The result showed that intraocular pressure was not significantly different between two grotips, and there was no significant intraocular pressure rise postoperatively in both groups.

MeSH Terms

Acetazolamide*
Anterior Chamber
Cataract Extraction*
Cataract*
Humans
Hyaluronic Acid
Intraocular Pressure
Acetazolamide
Hyaluronic Acid