J Korean Ophthalmol Soc.  1986 Aug;27(4):525-529.

The Effect of Lens Extraction on Hyaluronic Acid Concentration in Rabbit Vitreous

Affiliations
  • 1Department of Ophthalmology, Fatima Hospital, Taegu, Korea, Graduate School Kyungpook University, Korea.
  • 2Department of Ophthalmology, School of Medicine, Kyungpook University, Taegu, Korea.
  • 3Department of Biochemistry, College of Pharmaceutical Science, Hyosung University, Taegu, Korea.

Abstract

The cataract extraction is sometimes followed by postoperative complications related to changes in the vitreous. The lack of stability of vitreous in the aphakic eyes may be due not only to loss of the mechanical support of the lens but also to changes in the vitreous molecular composition. To define the effect of lens extraction on hyaluronic acid concentration in rabbit vitreous, six cases of rabbit eye were operated with ECCE and posterior capsulotomy equivalent to ICCE. In control rabbit group, hyaluronic acid concentration in vitreous was 202.3 +/- 77.8 ug/ml and the seventy days after surgical intervention, hyaluronic acid concentration in vitreous was 79.0 +/- 55.7 ug/ml. These result indicated that ECCE and posteror capsulotomy induced marked decrease of hyaluronic acid concentration in rabbit vitreous, which is statistically significant(p<0.05).


MeSH Terms

Cataract Extraction
Hyaluronic Acid*
Posterior Capsulotomy
Postoperative Complications
Hyaluronic Acid
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