J Korean Rheum Assoc.  2007 Sep;14(3):297-301. 10.4078/jkra.2007.14.3.297.

A Case of Systemic Lupus Erythematosus Associated with Kikuchi-Fujimoto's Disease

• Ahn CY
• Oh MG
• Ha JH
• Kim SH
• Hur JA

• KMID: 2202182
• DOI: http://doi.org/10.4078/jkra.2007.14.3.297

Abstract

Kikuchi-Fujimoto's disease (KFD) is a rare self-limiting necrotizing lymphadenitis found mainly in young women. Patients typically present with lymphadenopathy and often with a high fever. The etiology of the disease remains unknown, but various infection and autoimmune processes have been postulated to be the cause. We report here on a 22-year-old female with 7-year history of systemic lupus erythematosus presented with high fever and many enlarged cervical lymph nodes. Neck computed tomography scan showed multiple lymphadenopathies and KFD was proven by under sonographic guidance percutaneous needle biopsy.

Keyword

Kikuchi-Fujimoto's disease; Systemic lupus erythematosus; Lymphadenopathy

MeSH Terms

Biopsy, Needle
Female
Fever
Histiocytic Necrotizing Lymphadenitis*
Humans
Lupus Erythematosus, Systemic*
Lymph Nodes
Lymphadenitis
Lymphatic Diseases
Neck
Ultrasonography
Young Adult

Figure

• 

  Fig. 1. Neck computed tomography (CT) scan showed multiple lymphadenopathies.

• 

  Fig. 2. Extensive degenerative changes such as karyor- rhexis, pyknosis, and karyolysis (Papanicolau, X40).

• 

  Fig. 3. Extensive degenerative changes such as karyor- rhexis, pyknosis, and karyolysis (Papanicolau, X200).

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