J Korean Rheum Assoc.  2009 Mar;16(1):33-37. 10.4078/jkra.2009.16.1.33.

A Case of Multiple Gastric Carcinoid in a Woman with Systemic Lupus Erythematosus

• Song YJ
• Her MY
• Kim TH
• Kim JH
• Kim DY
• Lee SH
• Yoon HK

• KMID: 2202138
• DOI: http://doi.org/10.4078/jkra.2009.16.1.33

Abstract

Gastric carcinoid tumor is a rare neoplasm and it accounts for only 0.3% of all the gastric neoplasms. Gastric carcinoid tumor has high incidence in patients who are aged between 50 and 70 years, and it usually develops over a long period of time. Type I gastric carcinoid tumors are associated with autoimmune atrophic gastritis and pernicious anemia, and there are a few cases of gastric carcinoids in patients with other autoimmune diseases like Sjogren's syndrome and autoimmune thyroiditis. Here, we report on a case of recurrent type I gastric carcinoid tumors in a 42-years old woman who suffered with systemic lupus erythematosus.

Keyword

Systemic lupus erythematosus; Gastric carcinoid tumor; Autoimmune disorder

MeSH Terms

Aged
Anemia, Pernicious
Autoimmune Diseases
Carcinoid Tumor
Female
Gastritis, Atrophic
Humans
Incidence
Lupus Erythematosus, Systemic
Sjogren's Syndrome
Stomach Neoplasms
Thyroiditis, Autoimmune

Figure

• 

  Fig. 1. Endoscopic finding of the stomach. Approximately 0.6∼0.8 cm sized multiple reddish fixed elevated tumors were noted at the great curvature side and the anterior wall of the middle and proximal body of the stomach.

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  Fig. 2. Microscopic findings of the gastric biopsy. In the lamina propria, there were irregular cord-like infiltrations of tumor cells (A) and positive reaction for synaptophysin (B) (A: Hematoxylin and eosin stain, ×100, B: Immunohistochemical stain for synpatophysin, ×100).

Reference

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