J Korean Radiol Soc.
1997 Oct;37(4):571-573.
Experimental Model of Arteriovenous Fistula in Pigs
- Affiliations
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- 1Department of Diagnostic Radiology, University of Ulsan College of Medicine.
- 2Department of Thoracic Surgery, University of Ulsan College of Medicine.
- 3Department of Diagnostic Pathology, University of Ulsan College of Medicine.
- 4Asan Institute for Life Sciences.
- 5Department of Radiology, College of Medicine, Inha University.
Abstract
- PURPOSE
To establish an experimental model of arteriovenous fistula in pigs.
MATERIALS AND METHODS
Ten fistulas were created in eight pigs, and angiography was performed 3 to 5 days after surgery. A follow-up angiogram of three fistulas was obtained 2 to 12 weeks later. In one animal, pathologic examination showed occlusion 8 weeks after a successful operation.
RESULTS
Eight angiograms of nine fistulas in seven pigs were obtained; one animal died due to cardiac failure. In six pigs, high-flow fistulas were shown to be present, and in two, the fistulas were slow flow; a pseudoaneurysm was seen in one. A follow-up angiogram obtained in three cases showed occlusion of the fistula. Pathologic examination of one animal showed fibrosis in the occluded portion of the fistula.
CONCLUSION
An arteriovenous fistula model was surgically established in 80% of cases; during follow-up, three fistulas were seen to be occluded due to fibrosis. This model can therefore be used within one week of surgery.
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