J Korean Pediatr Cardiol Soc.  2006 Dec;10(4):426-435.

Assessment of Systemic Right Ventricular Function using Strain/Strain Rate in Congenitally Corrected Transposition of the Great Arteries

• Kim SH
• Huh J
• Kang IS
• Lee HJ
• Park SW

Abstract

PURPOSE: In patients with the congenitally corrected transposition of great arteries (CCTGA), systemic ventricle tends to be hypertrophic due to longstanding systemic high pressure that may lead to dysfunction of ventricle. The aim of this study was to assess the global and segmental wall function of systemic right ventricle in CCTGA.
METHODS
Twelve patients with the CCTGA patients were enrolled. Ejection fraction of systemic right ventricle, myocardial performance index (MPI), strain and strain rate were assessed.
RESULTS
The median age was 32.5 years with a range of 4 to 66 years. Ejection fraction (EF) using M-mode and Simpsons method was significantly lower in the CCTGA patients (48.5+/-4.6% and 51.2+/-4.1%, respectively, vs 63.7+/-3.6% and 66.6+/-3.8% respectively). 5 patients had diastolic dysfunction (3/12; pseudo-normalization pattern, 2/12; relaxation abnormality). Strain and strain rate revealed segmental systemic right ventricle dysfunction, and were lower in the CCTGA patients at mid and apical segment of septum and apical segment of anterior wall. The extent of dysfunctional segment was related to the age and MPI.
CONCLUSION
There was global dysfunction in the CCTGA patients and it was related with age. Segmental dysfunction was especially shown at mid and apical segment of septum and apical segment of anterior wall and more frequently at apical segment of each wall. The extent of dysfunctional segment was related with age.

Keyword

Transposition of great vessels; Right ventricle; Strain

MeSH Terms

Arteries*
Heart Ventricles
Humans
Relaxation
Transposition of Great Vessels
Ventricular Function, Right*