J Menopausal Med.  2015 Aug;21(2):82-88. 10.6118/jmm.2015.21.2.82.

Factors Associated with Mammographic Density in Postmenopausal Women

Affiliations
  • 1Department of Obstetrics and Gynecology, Faculty of Medicine, Bozok University, Yozgat, Turkey. emelkiyak@hotmail.com
  • 2Department of Surgery, Faculty of Medicine, Bozok University, Yozgat, Turkey.
  • 3Department of Obstetrics and Gynecology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
  • 4Department of Radiology, Faculty of Medicine, Bozok University, Yozgat, Turkey.

Abstract


OBJECTIVES
Breast density increases the risk of breast cancer, but also in the interpretation of mammography is also important. This study examine the risk factors affecting breast density in postmenopausal women.
METHODS
Between January 2013 and January 2014, 215 patients admitted to The Clinics of Gynecology and Obstetrics with complaints of menopause were taken. According to the results of mammography, Group I (non-dense, n = 175) and Group II (dense, n = 40) were created. The informations of the caseswere analyzed retrospectively.
RESULTS
In Group I, body mass index (BMI), number of pregnancies, parity were significantly higher than group II (P < 0.05). In group II, the withdrawal period of menstruation and progesterone levels were significantly higher (P < 0.05). In logistic regression analysis, BMI for dense breasts and number of pregnancies were found to be an independent risk factor (P < 0.05).
CONCLUSION
Increased BMI, pregnancy and parity, result of reduction in density , but longer duration of menopause and increased progesterone cause an increase in density. BMI and the number of pregnancy was found to be independent risk factors for reducing breast density.

Keyword

Mammary glands human; Mammography; Postmenopause

MeSH Terms

Body Mass Index
Breast
Breast Neoplasms
Female
Gynecology
Humans
Logistic Models
Mammography
Menopause
Menstruation
Obstetrics
Parity
Postmenopause
Pregnancy
Progesterone
Retrospective Studies
Risk Factors
Progesterone

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Winnie Lai-Sheung Cheng, Florence MF Wong
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