J Korean Radiol Soc.  2000 Jul;43(1):31-37. 10.3348/jkrs.2000.43.1.31.

Measurement of Myocardial Perfusion with Electron Beam Tomography: Comparison with 99m Tc-MIBI Scan

• Lee SK
• Jeon TJ
• Lee JD
• Huh KB
• Choi JY
• Yoo SJ
• Choi BW
• Youn BB
• Kang HC
• Choe KO

• KMID: 2200695
• DOI: http://doi.org/10.3348/jkrs.2000.43.1.31

Abstract

PURPOSE: To compare the accuracy with which electron beam tomography (EBT) and 99m Tc-MIBI scanning measure myocardial perfusion valve.
MATERIALS AND METHODS
Twenty-two subjects [normal volunteers (n = 6), patients in whom ischemic heart disease was diagnosed (n = 5), and those in whom ischemic heart disease was suspected but who were found to be normal (n = 11)] were involved in this study. EBT was performed after bolus injection of contrast media (50 ml of Iopamiro 370 or Optiray 350, 3 ml/sec). The myocardium was divided into 16 segments according to the classification devised by the American Society of Echocardiography, and each myocardial perfusion value was calculated by post-image processing. A pharmacologic stress test was performed in all subjects except four patients with acute myocardial infarction, and myocardial perfusion reserve ratios were assessed. Single photon emission computed tomography (SPECT) was performed after the injection of 20 mCi of 99m Tc-MIBI. Any segments with moderate to severe photon defect on visual analysis of SPECT were identified and perfusion values determined by EBT in normal and ischemic segments were compared.
RESULTS
No difference in myocardial perfusion was found between volunteers and the suspected group. Their perfusion values were 0.71 +/-0.14 ml/g/min in the resting state and 1.16 +/-0.24 ml/g/min on the stress test and the myocardial perfusion reserve ratio was, therefore, 1:1.68 +/-0.38. In ischemic patients, 99m Tc-MIBI scanning revealed a perfusion defect in 28 segments, and on EBT the measurement obtained was 0.54 +/-0.19 ml/g/min. The remaining 324 perfusion segments shown by SPECT to be normal showed a perfusion value of 0.79 +/-0.22 ml/g/min on EBT.
CONCLUSION
Compared with 99mTc-MIBI scanning, the measurement of myocardial perfusion by EBT provides absolute quantification of perfusion value and more detailed anatomic information.

Keyword

Myocardium, blood supply Myocardium; Electron Beam Tomography Myocardium; 99mTc-MIBI scan; Myocardium, ischemia

MeSH Terms

Classification
Contrast Media
Echocardiography
Exercise Test
Humans
Iopamidol
Myocardial Infarction
Myocardial Ischemia
Myocardium
Perfusion*
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed*
Volunteers
Contrast Media
Iopamidol