J Korean Radiol Soc.  2004 Mar;50(3):213-215. 10.3348/jkrs.2004.50.3.213.

Breast Gigantism Induced by D-Penicillamine: Case Report

Affiliations
  • 1Department of Radiology, Asan Medial Center, University of Ulsan College of Medicine, Korea. hhkim@amc.seoul.kr

Abstract

D-penicillamine, a chelating agent of copper, is the drug of choice for the treatment of Wilson's disease. Breast enlargement is a rare complication arising from its use, and we report a case of breast gigantism which developed after it had been used for ten months to treat this condition. Mammography demonstrated bilaterally enlarged dense breasts; ultrasonography, similarly, demonstrated enlargement, revealing the presence of a mass, shown at biopsy to be benign, in the left one.

Keyword

Breast gigantism; D-penicillamine, breast enlargement; Breast

MeSH Terms

Biopsy
Breast*
Copper
Gigantism*
Hepatolenticular Degeneration
Mammography
Penicillamine*
Ultrasonography
Copper
Penicillamine

Cited by  2 articles

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Ku Sang Kim, Sun Mi Kim, Mijung Jang, Joon Seok Hong, Sung-Won Kim
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A case of Breast Gigantism in a Patient with Wilson's Disease treated by Penicillamine
Jeong Eon Lee, Hyuk Jai Shin, Sung Eun Hwang, Ki Tae Hwang, Seung Keun Oh, Yeo-Kyu Youn, Dong-Young Noh, Sung-Won Kim, Wonshik Han
J Breast Cancer. 2006;9(1):69-72.    doi: 10.4048/jbc.2006.9.1.69.

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