J Korean Soc Transplant.
1997 May;11(1):151-156.
A Case of Fulminant Hepatic Failure Secondary to Non-thrombotic Graft Infarction After Living Related Liver Transplantation
- Affiliations
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- 1Department of Surgery, Asan Medical Center, Ulsan University of Medical School, Seoul, Korea.
- 2Department of Anesthesiology, Asan Medical Center, Ulsan University of Medical School, Seoul, Korea.
- 3Department of Pediatrics, Asan Medical Center, Ulsan University of Medical School, Seoul, Korea.
Abstract
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Non-thrombotic graft infarction of the liver following orthotopic liver transplantation(OLT) occurs infrequently during an otherwise uneventful recovery 1 week after OLT. The typical clinical presentation is an uneventful initial postoperative recovery, followed by sudden deterioration of allograft function in the absence of vascular thrombosis with rapid progression to graft failure. The characteristic pathological change is massive hemorrhagic necrosis with only mild portal tract inflammation. The pathogenesis and definite etiologies were until not clear. Recently we experienced non-thrombotic graft infarction on the 8th day after liver transplantation from a 51-year-old living donor to his 17-year-old daughter.