J Korean Soc Ther Radiol.  1990 Jun;8(1):65-73.

Treatment Results and Prognostic Factors in the Management of Locoregional Recurrent Breast Carcinoma

• Moon SR
• Lee HS
• Kim GE
• Ahn KJ
• Suh CO
• Loh JJ
• Min JS
• Lee KS
• Kim BS
• Noh JK
• Koh EH

Abstract

Between January, 1974 and December 1986, fifty eight patients with locoregional recurrent breast carcinoma who did not have evidence of distant metastasis after initial treatment of surgery with or without adjuvant chemotherapy were treated with radiation therapy. Among them, five patients were excluded from this study because of incomplete record or incomplete treatment. The 5-year overall survival and disease free survival from the time of locoregional recurrence was 27% and 15% respectively. In univariate analysis of prognostic variables, the clinical stage at initial diagnosis, recur duration, number of recurrence sites, size of recurrences, response to the treatment, remission duration were all found to have no significant effect on survival or disease free survial. On the other hand, menopausal status at initial diagnosis, number of positive node at initial surgery, whether or not the use of adjuvant chemotherapy after initial mastectomy had definite prognositc significance. In multivariate analysis of prognostic variables, remission duration, menopausal status at diagnosis, number of axillary node at mastectomy had definite prognostic significance. On the other hand, remission duration more than 12 months, premenopaus at initial mastectomy, less than four positive axillary lymph nodes at mastectomy predicted a good prognosis.

Keyword

Radiotherapy; Local recerrent breast carcinoma; Prognostic factor

MeSH Terms

Breast Neoplasms*
Breast*
Chemotherapy, Adjuvant
Diagnosis
Disease-Free Survival
Hand
Humans
Lymph Nodes
Mastectomy
Multivariate Analysis
Neoplasm Metastasis
Prognosis
Radiotherapy
Recurrence