J Korean Acad Periodontol.  2000 Jun;30(2):277-286. 10.5051/jkape.2000.30.2.277.

The Comparison of the Effects on the Regeneration with Xenografts on the Furcation Involvement in Beagle Dogs

• Cho JS
• Kim JY
• Chung CH
• Yim SB

• KMID: 2191811
• DOI: http://doi.org/10.5051/jkape.2000.30.2.277

Abstract

For the regeneration of osseous defect on the furcation area, autogeneous bone graft has been primarily used. But it has the limitation of donor site, additive surgical operation etc. Recently anorganic xenogenic bone graft materials of removing all organic components are commonly used for the regeneration of periodontal defects. This study was the comparison of the effect on the regeneration with two types xenografts(Bio-oss(R) and Ca-P thin coated Bovine bone powder) on the furcation involvement in Beagle dogs. After surgically induced chronic periodontitis in bifurcation area of premolar, Bio-oss(R) and Ca-P BBP were grafted on the osseous defects. Tissue blocks including defects with soft tissues were harvested following a four-& eight-week healing interval and prepared for histologic analysis. The results of this study were as follows: 1. Bio-oss(R) group: there were significant differences among the Bio-oss? group at 4weeks and 8weeks, but the control group had various appearances : new bone formation, resorption of graft materials by multinuclear giant cells, connective tissue cells intervention in the bone graft sites etc. 2. Ca-P BBP group: lots of new bone formation were observed but the arrangement of periodontal ligament was not completed at 4weeks. New bone were replaced mature bone and the periodontal ligaments showed the functional arrangement at 8weeks. 3. By reason of undergrowing the epithelium within the osseous defects, new bone formation was not happened in the upper area of bifurcation in Bio-oss(R) group. 4. In Ca-P BBP group, epithelial undergrowth was not seen and generally showed much more new bone formation. 5. Ca-P BBP group showed the osteocyte-like cells at the inner portion of the graft materials 6. Both groups were similar to resorptive appearances of graft materials, but Ca-P BBP group had the better effects of osteoconduction.

MeSH Terms

Animals
Bicuspid
Bone Regeneration
Chronic Periodontitis
Connective Tissue Cells
Dogs*
Epithelium
Giant Cells
Heterografts*
Humans
Osteogenesis
Periodontal Ligament
Regeneration*
Tissue Donors
Transplants