J Korean Neurol Assoc.
2012 Nov;30(4):301-304.
Rheumatoid Meningitis: Neurologic Manifestation and Pathologic Findings
- Affiliations
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- 1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea. kheo@yuhs.ac
- 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man with the history of rheumatoid arthritis presented with intermittent left leg weakness, seizures and later developed fever and confusion. Brain MRI demonstrated leptomeningeal enhancement in right fronto-parietal area. Brain biopsy revealed multifocal suppurative inflammation. After aggressive immunosuppressive treatment, he had gradually recovered and the lesion was reduced on a follow-up MRI.
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