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Development and Validation of MRI-Based Radiomics Models for Diagnosing Juvenile Myoclonic Epilepsy

Kim KM, Hwang H, Sohn B, Park K, Han K, Ahn SS, Lee W, Chu MK, Heo K, Lee SK

Objective: Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed to develop and...
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Anti-Oral Microbial Activity and Anti-Inflammatory Effects of Rosmarinic Acid in Lipopolysaccharide-Stimulated MC3T3-E1 Osteoblastic Cells on a Titanium Surface

Jeong MJ, Lim DS, Heo K, Jeong SJ

Background: The purpose of this study was to investigate the anti-oral microbial activity and anti-inflammatory effects of rosmarinic acid (RA) in lipopolysaccharide (LPS)-stimulated MC3T3-E1 osteoblastic cells on a titanium (Ti)...
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Inhibitory Effects on Oral Microbial Activity and Production of Lipopolysaccharides-Induced Pro-Inflammatory Mediators in Raw264.7 Macrophages of Ethanol Extract of Perilla flutescens (L.) Britton

Jeong MJ, Lim DS, Lee MH, Heo K, Kim HH, Jeong SJ

Background: The leaves of Perilla frutescens, commonly called perilla and used for food in Korea, contain components with a variety of biological effects and potential therapeutic applications. The purpose of...
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A Case of Rapid Eye Movement Sleep-Related Bradyarrhythmia Syndrome with Severe Obstructive Sleep Apnea Syndrome

Lee DH, Kim TH, Heo K

A close relationship has emerged between obstructive sleep apnea (OSA) and cardiac arrhythmia. However, transient sinus arrest or atrioventricular (AV) conduction disturbance during rapid eye movement (REM) sleep was rarely...
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Posterior Shoulder Instability in the Patients with Bilateral Congenital Absence of Long Head of Biceps Tendon: A Case Report

Yoon SH, Heo K, Yoo JS, Kim SJ, Seo JB

Rare cases of a congenital absence of the long head of the biceps tendon (LHBT) have been reported, and its incidence is unknown. In a literature review of the congenital...
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A De Novo RAPGEF2 Variant Identified in a Sporadic Amyotrophic Lateral Sclerosis Patient Impairs Microtubule Stability and Axonal Mitochondria Distribution

Heo K, Lim SM, Nahm M, Kim YE, Oh KW, Park HT, Ki CS, Kim SH, Lee S

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is frequently linked to microtubule abnormalities and mitochondrial trafficking defects. Whole exome sequencing (WES) of patient-parent trios has proven to...
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Effect of Surgical-Site, Multimodal Drug Injection on Pain and Stress Biomarkers in Patients Undergoing Plate Fixation for Clavicular Fractures

Yoo JS, Heo K, Kwon SM, Lee DH, Seo JB

BACKGROUND: Surgical-site, multimodal drug injection has recently evolved to be a safe and useful method for multimodal pain management even in patients with musculoskeletal trauma. METHODS: Fifty consecutive patients who underwent...
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First Molecular Diagnosis of a Patient with Unverricht-Lundborg Disease in Korea

Kim KH, Song JS, Park CW, Ki CS, Heo K

Unverricht-Lundborg disease (ULD) is a form of progressive myoclonus epilepsy characterized by stimulation-induced myoclonus and seizures. This disease is an autosomal recessive disorder, and the gene CSTB, which encodes cystatin...
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Ultrasound-Guided Percutaneous Needle Fasciotomy after Steroid Injection for Dupuytren's Contracture

Yoo JS, Heo K, Kim SJ, Park KH, Kim JP

PURPOSE: The purpose of this study was to report outcomes of ultrasound-guided percutaneous needle fasciotomy (USPNF) after intralesional steroid injections (SI). METHODS: Tirty-two fingers (fourteen patients) treated by USPNF 4 weeks...
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Management of Alcohol Withdrawal Syndrome and Alcohol Withdrawal Seizure

Heo K, Cho YJ, Eun SH, Lim SC, Lee J, Song P

Alcohol withdrawal syndrome (AWS) is a common condition occurring after intentional or unintentional abrupt cessation of alcohol in an alcohol-dependent individual. AWS represents a major problem in our society and...
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Dynamic relocalization of NHERF1 mediates chemotactic migration of ovarian cancer cells toward lysophosphatidic acid stimulation

Oh YS, Heo K, Kim EK, Jang JH, Bae SS, Park JB, Kim YH, Song M, Kim SR, Ryu SH, Kim IH, Suh PG

NHERF1/EBP50 (Na⁺/H⁺ exchanger regulating factor 1; Ezrin-binding phosphoprotein of 50 kDa) organizes stable protein complexes beneath the apical membrane of polar epithelial cells. By contrast, in cancer cells without any fixed...
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Two Cases of Sleep-Related Painful Erection

Cho KH, Kim HI, Heo K, Cho YJ

Sleep-related painful erection (SRPE) is characterized by deep penile pain accompanied with erection occurring rapid eye movement (REM) movement period. Two (47-year-old and 40-year-old, respectively) male visited with the complaint...
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Typical Aura without Headache Presenting Intermittent Transient Visual Symptom

Kim HK, Kim DE, Heo K

No abstract available.
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Clinical Utility of Bone Marrow Study in Gaucher Disease: A Case Report of Gaucher Disease Type 3 With Intractable Myoclonic Seizures

Rim JH, Baik M, Yoon SO, Heo K, Song J

No abstract available.
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Sleep Disorder Caused by Proctalgia Fugax

Kim KH, Cho KH, Cho YJ, Heo K

Proctalgia fugax is characterized by severe cramp like pain in anorectal area. It is a common functional gastrointestinal disorder, but symptoms of proctalgia fugax are usually too brief and mild...
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Glossopharyngeal Neuralgia Secondary to Tongue Squamous Cell Carcinoma

Lee DH, Kim KM, Lee Y, Yi H, Cho YJ, Lee BI, Heo K

No abstract available.
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Efficacy of Phenytoin for Nocturnal Muscle Cramps: A Preliminary Study

Kim KM, Lee DH, Lee Y, Yi H, Cho YJ, Lee BI, Heo K

BACKGROUND: Nocturnal muscle cramps are sudden, involuntary, painful muscle contractions that occur in the night and are accompanied by hardening of the muscles. Many symptomatic treatments have been introduced for...
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Prophylactic Effect of Erythropoietin Injection to Prevent Acute Mountain Sickness: An Open-Label Randomized Controlled Trial

Heo K, Kang JK, Choi CM, Lee MS, Noh KW, Kim SB

This study was performed to evaluate whether increasing hemoglobin before ascent by prophylactic erythropoietin injections prevents acute mountain sickness (AMS). This open-label, randomized, controlled trial involved 39 healthy volunteers with...
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Rheumatoid Meningitis: Neurologic Manifestation and Pathologic Findings

Lee KJ, Yim SH, Kim DW, Kim SW, Lee MK, Cho YJ, Lee BI, Heo K, Kim SH

  • KMID: 2191523
  • J Korean Neurol Assoc.
  • 2012 Nov;30(4):301-304.
Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man...
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The Localizing and Lateralizing Value of Auras in Lesional Partial Epilepsy Patients

Ye BS, Cho YJ, Jang SH, Lee MK, Lee BI, Heo K

PURPOSE: We investigated the localizing and lateralizing values of auras in patients with lesional partial epilepsy on an outpatient basis. MATERIALS AND METHODS: A total of 276 subjects were retrospectively selected...
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