J Korean Assoc Oral Maxillofac Surg.
2000 Oct;26(5):437-445.
Comparative Study of Wound Healing Following Partial Glossectomy of Rat Tongue Using CO2 Laser and Scalpel
- Affiliations
-
- 1Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University.
- 2Department of Pathology, College of Medicine, Soonchunhyang University.
Abstract
- OBJECT: This study is focused on the comparison between CO2 laser and scalpel by examining the overal process of wound healing after partial glossectomy of rats so that the result from the research could be easily applied to actual clinical environment.
METHOD AND MATERIAL: In this research, 2mm defect was formed on both lateral borders of the tongue of rats by using CO2 laser and scalpel respectively. 4rats were sacrified each time on the 1st, 2nd, 4th, 7th, 14th and 21th day according to a general method. After fabricating 5 micrometer paraffin specimen, H&E staining and MT staining were performed.
RESULTS
Compared to scalpel, wound healing by CO2 laser leads to a earlier initiation of vascular proliferation and re-epithelization. Therefore, some influence is exerted on the early stage of wound healing. However, the two methods seem to undergo the similar healing process.
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