J Korean Assoc Oral Maxillofac Surg.  2005 Jun;31(3):279-282.

Multiple langerhans cell histiocytosis at the lung and mandible: Case report

• Hwang JH
• Lee BK

Abstract

Hitiocytosis X, recently termed Langergans cell histiocytosis, is a rare disease histologically characterized by an abnormal proliferation of histiocytes, and of which the pathophysiology is still ambiguous. The clinical presentation is highly varied. Typically, there is a solitary or multiple bony involvements, and less frequently, lesions are found in other organs such as the lungs, liver, lymph nodes, skin, and mucosae. Interestingly, so far, there has been no report which shows multiple developments in both soft and hard tissues. In this report, we present a case of hitiocytosis X in both mandible and lung. This may provide some information for understanding the pathophysilogy of the histiocytosis X.

Keyword

Histiocytosis X; Surgical curettage; Eosinophilic granuloma

MeSH Terms

Eosinophilic Granuloma
Histiocytes
Histiocytosis
Histiocytosis, Langerhans-Cell*
Liver
Lung*
Lymph Nodes
Mandible*
Mucous Membrane
Rare Diseases
Skin